II मार्गदर ्शक II
Scientific Discoveries:
-
We, for the first time, invented this phenomenon "Enantiomer Self-disproportionation (ESD)" for the separation of non-racemic mixtures of non-fluorinated compounds. It is not only limited to fluorinated compounds. We have discovered and given a third possible mechanism for ESD. Enantiomer self-disproportionation is a process in stereochemistry describing the separation of a non-racemic mixture of enantiomer in an enantio-enriched fraction and more racemic fractions as a result of the heterochiral, homochiral and mixture of both the aggregates.
-
New Patented silica-supported (i) Chiral amino-alcohol and (ii) its metal complex based chiral column packing material (HPLC column) for separation of racemic medicines, drug intermediates, and reagents.
Youtube Channel:
Dr. Vishal J. Mayani
RESEARCH INTERESTS:
-
Chiral ligands & metal complexes for asymmetric heterogeneous catalysis.
-
Chiral resolution and enantiomer self-disproportionation.
-
Organic pharmaceuticals, radio-pharmaceuticals, and nanoparticles drug carriers.
-
Preparation of mesoporous materials, nano-reactors, and magnetic materials.
-
Synthesis of organic-inorganic hybrid metal-carbon silica composite material polymeric materials and its catalytic applications.
-
Biological evaluation of Pharmaceuticals (activities, diagnosis).
-
Organic-Inorganic Hybrid Materials for environment protection.
KEY RESEARCH Project involved/HanDled:
-
Chiral heterogeneous catalyst of aminoalcohol for asymmetric Henry reaction (Inorganic materials for diverse applications (CSIR Project No. NWP-0010).
-
Separation of non-racemic chiral organic compound using ‘Enantiomer Self-disproportionation’ chromatography (CSIR Project No. NWP-0010).
-
Development of organic-inorganic sorbents for enantioseparation of racemic compounds (Development of polymeric materials, CSIR Project No. COR-0004).
-
Development of chiral MPLC/HPLC columns using chiral ligand stationary phase (CLSP) & chiral ligand metal stationary phase (CLMSP) for chiral resolution (CSIR Project No. COR-0004).
-
Synthesis of chiral hydrocyanins as intermediates for industrial important bioactive compounds through chiral catalytic route (DST Project No. GAP-0092).
-
Development of carbon metal nano-reactors from inexpensive petroleum residue and its multifunctional applications (catalysis, energy storage, electrode, etc.)
-
Synthesis and evaluation of folate immobilized radioactive 198Au@NSB (Nano silica ball) for the diagnosis of cancer.
-
Development of 44Sc based Radiopharmaceuticals for the Diagnosis of Tumors (Korea MEST Project N. K-2012-A0173-00022).
-
Air Quality Monitoring for the Numaligarh Refinery Limited (Environmental Impact Assessment (EIA) project).
-
Water Quality Assessment of the Deepar Beel (North Eastern Space Application Centre (NESAC) project).
-
Monitoring of Arsenic and Fluoride in Groundwater in Sensitive Blocks of Assam (Assam Agricultural Competitiveness Project (AACP) of Agricultural Rural Infrastructure and Agricultural Services Society).
-
Development of carbon metal nano-reactors from inexpensive petroleum residue and its multifunctional applications (catalysis, energy storage, electrode, etc.).